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TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration

Choroidal neovascularization(CNV) is the most severe complication in Age-related macular degeneration(AMD) and the most common cause of irreversible blindness in the elderly in developed world. The aim of this study was to identify the effect of transforming growth factor-β(TGF-β) and Smad2/3-VEGF/T...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Ma, Wei, Han, Song, Meng, Zhaoyang, Zhao, Lu, Yin, Yi, Wang, Yanling, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575286/
https://www.ncbi.nlm.nih.gov/pubmed/28852052
http://dx.doi.org/10.1038/s41598-017-10124-4