Orchestrated Domain Movement in Catalysis by Cytochrome P450 Reductase

NADPH-cytochrome P450 reductase is a multi-domain redox enzyme which is a key component of the P450 mono-oxygenase drug-metabolizing system. We report studies of the conformational equilibrium of this enzyme using small-angle neutron scattering, under conditions where we are able to control the redo...

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Detalles Bibliográficos
Autores principales: Freeman, Samuel L., Martel, Anne, Raven, Emma L., Roberts, Gordon C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575293/
https://www.ncbi.nlm.nih.gov/pubmed/28852004
http://dx.doi.org/10.1038/s41598-017-09840-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575293/
https://www.ncbi.nlm.nih.gov/pubmed/28852004
http://dx.doi.org/10.1038/s41598-017-09840-8

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