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The Role of Na+/Ca2+ Exchanger 1 in Maintaining Ductus Arteriosus Patency

Patency of the ductus arteriosus (DA) is crucial for both fetal circulation and patients with DA-dependent congenital heart diseases (CHD). The Na(+)/Ca(2+) exchanger 1 (NCX1) protein has been shown to play a key role in the regulation of vascular tone and is elevated in DA-dependent CHD. This curre...

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Detalles Bibliográficos
Autores principales: Li, Minghui, Jiang, Chuan, Ye, Lincai, Wang, Shoubao, Zhang, Haibo, Liu, Jinfen, Hong, Haifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575298/
https://www.ncbi.nlm.nih.gov/pubmed/28852106
http://dx.doi.org/10.1038/s41598-017-10377-z