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Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3

Glypican-3 (GPC3) is a promising new marker for hepatocellular carcinoma, but the reported values for serum GPC3 differ markedly between currently available kits. Here we isolated Affimer non-antibody binding proteins against GPC3 by phage display and developed a new sandwich chemiluminescence immun...

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Detalles Bibliográficos
Autores principales: Xie, Chunmei, Tiede, Christian, Zhang, Xuanyi, Wang, Congrong, Li, Zhixiong, Xu, Xiao, McPherson, Michael J., Tomlinson, Darren C., Xu, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575301/
https://www.ncbi.nlm.nih.gov/pubmed/28852111
http://dx.doi.org/10.1038/s41598-017-10083-w