A novel three-dimensional culture system maintaining the physiological extracellular matrix of fibrotic model livers accelerates progression of hepatocellular carcinoma cells

Liver fibrosis is characterized by the progressive accumulation of extracellular matrix (ECM) and is a strong predictor of hepatocellular carcinoma (HCC) development and progression. However, the effect of ECM in fibrotic livers on HCC cells is poorly understood. The aims of this study were to creat...

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Detalles Bibliográficos
Autores principales: Miyauchi, Yuya, Yasuchika, Kentaro, Fukumitsu, Ken, Ishii, Takamichi, Ogiso, Satoshi, Minami, Takahito, Kojima, Hidenobu, Yamaoka, Ryoya, Katayama, Hokahiro, Kawai, Takayuki, Yoshitoshi-Uebayashi, Elena Yukie, Kita, Sadahiko, Yasuda, Katsutaro, Sasaki, Naoya, Uemoto, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575302/
https://www.ncbi.nlm.nih.gov/pubmed/28851916
http://dx.doi.org/10.1038/s41598-017-09391-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575302/
https://www.ncbi.nlm.nih.gov/pubmed/28851916
http://dx.doi.org/10.1038/s41598-017-09391-y

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