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Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage

Farnesoid X receptor (FXR) activation has been reported to reduce inflammation and oxidative stress. Because both inflammation and oxidative stress are critical for tissue destruction during kidney ischemia reperfusion (I/R) injury, we investigated the protective role of FXR against kidney damage in...

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Detalles Bibliográficos
Autores principales: Gai, Zhibo, Chu, Lei, Xu, Zhenqiang, Song, Xiaoming, Sun, Dongfeng, Kullak-Ublick, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575310/
https://www.ncbi.nlm.nih.gov/pubmed/28852062
http://dx.doi.org/10.1038/s41598-017-10168-6