Upregulation of prefrontal metabotropic glutamate receptor 5 mediates neuropathic pain and negative mood symptoms after spinal nerve injury in rats

Patients with chronic pain easily accompany the negative mood symptoms such as depression and anxiety, and these disturbances in turn affect the aversive perception of pain. However, the underlying mechanisms are largely unknown. We hypothesized that the alteration of metabotropic glutamate receptor...

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Detalles Bibliográficos
Autores principales: Chung, Geehoon, Kim, Chae Young, Yun, Yeong-Chan, Yoon, Sang Ho, Kim, Myoung-Hwan, Kim, Yu Kyeong, Kim, Sang Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575341/
https://www.ncbi.nlm.nih.gov/pubmed/28851991
http://dx.doi.org/10.1038/s41598-017-09991-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575341/
https://www.ncbi.nlm.nih.gov/pubmed/28851991
http://dx.doi.org/10.1038/s41598-017-09991-8

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