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A broad range quorum sensing inhibitor working through sRNA inhibition

For the last decade, chemical control of bacterial virulence has received considerable attention. Ajoene, a sulfur-rich molecule from garlic has been shown to reduce expression of key quorum sensing regulated virulence factors in the opportunistic pathogen Pseudomonas aeruginosa. Here we show that t...

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Detalles Bibliográficos
Autores principales: Jakobsen, Tim H., Warming, Anders N., Vejborg, Rebecca M., Moscoso, Joana A., Stegger, Marc, Lorenzen, Frederik, Rybtke, Morten, Andersen, Jens B., Petersen, Rico, Andersen, Paal Skytt, Nielsen, Thomas E., Tolker-Nielsen, Tim, Filloux, Alain, Ingmer, Hanne, Givskov, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575346/
https://www.ncbi.nlm.nih.gov/pubmed/28851971
http://dx.doi.org/10.1038/s41598-017-09886-8