Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2

Metabolic diseases like diabetes mellitus cause bone healing deficiencies. We found significant impairment of bone regeneration, osteogenic differentiation and proliferation in diabetic bone. Moreover recent studies suggest a highly underestimated importance of GDF8 (Myostatin) in bone metabolism. O...

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Detalles Bibliográficos
Autores principales: Wallner, Christoph, Jaurich, Henriette, Wagner, Johannes Maximilian, Becerikli, Mustafa, Harati, Kamran, Dadras, Mehran, Lehnhardt, Marcus, Behr, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575348/
https://www.ncbi.nlm.nih.gov/pubmed/28852138
http://dx.doi.org/10.1038/s41598-017-10404-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575348/
https://www.ncbi.nlm.nih.gov/pubmed/28852138
http://dx.doi.org/10.1038/s41598-017-10404-z

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