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Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2
Metabolic diseases like diabetes mellitus cause bone healing deficiencies. We found significant impairment of bone regeneration, osteogenic differentiation and proliferation in diabetic bone. Moreover recent studies suggest a highly underestimated importance of GDF8 (Myostatin) in bone metabolism. O...
Autores principales: | Wallner, Christoph, Jaurich, Henriette, Wagner, Johannes Maximilian, Becerikli, Mustafa, Harati, Kamran, Dadras, Mehran, Lehnhardt, Marcus, Behr, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575348/ https://www.ncbi.nlm.nih.gov/pubmed/28852138 http://dx.doi.org/10.1038/s41598-017-10404-z |
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