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Identification of butenolide regulatory system controlling secondary metabolism in Streptomyces albus J1074
A large majority of genome-encrypted chemical diversity in actinobacteria remains to be discovered, which is related to the low level of secondary metabolism genes expression. Here, we report the application of a reporter-guided screening strategy to activate cryptic polycyclic tetramate macrolactam...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575351/ https://www.ncbi.nlm.nih.gov/pubmed/28852167 http://dx.doi.org/10.1038/s41598-017-10316-y |