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A Total-variation Constrained Permutation Model for Revealing Common Copy Number Patterns
Variations in DNA copy number carry important information on genome evolution and regulation of DNA replication in cancer cells. The rapid development of single-cell sequencing technology enables exploration of gene-expression heterogeneity among single cells, providing important information on cell...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575355/ https://www.ncbi.nlm.nih.gov/pubmed/28851906 http://dx.doi.org/10.1038/s41598-017-09139-8 |