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Lineage-Restricted Mammary Stem Cells Sustain the Development, Homeostasis, and Regeneration of the Estrogen Receptor Positive Lineage

The mammary gland (MG) is composed of different cell lineages, including the basal and the luminal cells (LCs) that are maintained by distinct stem cell (SC) populations. LCs can be subdivided into estrogen receptor (ER)(+) and ER(−) cells. LCs act as the cancer cell of origin in different types of...

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Detalles Bibliográficos
Autores principales: Van Keymeulen, Alexandra, Fioramonti, Marco, Centonze, Alessia, Bouvencourt, Gaëlle, Achouri, Younes, Blanpain, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575359/
https://www.ncbi.nlm.nih.gov/pubmed/28813665
http://dx.doi.org/10.1016/j.celrep.2017.07.066