Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection

Sonic hedgehog (SHH) is a glycoprotein associated with development that is also expressed in the adult CNS and released after brain injury. Since the SHH receptors patched homolog‐1 and Smoothened are highly expressed on astrocytes, we hypothesized that SHH regulates astrocyte function. Primary mous...

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Detalles Bibliográficos
Autores principales: Ugbode, Christopher I., Smith, Imogen, Whalley, Benjamin J., Hirst, Warren D., Rattray, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575469/
https://www.ncbi.nlm.nih.gov/pubmed/28485896
http://dx.doi.org/10.1111/jnc.14064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575469/
https://www.ncbi.nlm.nih.gov/pubmed/28485896
http://dx.doi.org/10.1111/jnc.14064

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