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Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection
Sonic hedgehog (SHH) is a glycoprotein associated with development that is also expressed in the adult CNS and released after brain injury. Since the SHH receptors patched homolog‐1 and Smoothened are highly expressed on astrocytes, we hypothesized that SHH regulates astrocyte function. Primary mous...
Autores principales: | Ugbode, Christopher I., Smith, Imogen, Whalley, Benjamin J., Hirst, Warren D., Rattray, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575469/ https://www.ncbi.nlm.nih.gov/pubmed/28485896 http://dx.doi.org/10.1111/jnc.14064 |
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