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Activity‐Based Probes for HECT E3 Ubiquitin Ligases

Activity‐based probes (ABPs) have been used to dissect the biochemical/structural properties and cellular functions of deubiquitinases. However, their utility in studying cysteine‐based E3 ubiquitin ligases has been limited. In this study, we evaluate the use of ubiquitin‐ABPs (Ub‐VME and Ub‐PA) and...

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Detalles Bibliográficos
Autores principales: Byrne, Robert, Mund, Thomas, Licchesi, Julien D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575557/
https://www.ncbi.nlm.nih.gov/pubmed/28425671
http://dx.doi.org/10.1002/cbic.201700006