Daily oral administration of low‐dose methotrexate has greater antirheumatic effects in collagen‐induced arthritis rats

OBJECTIVES: Methotrexate (MTX) is administered once or thrice weekly to patients with rheumatoid arthritis (RA). Even though RA continually progresses, MTX is not administered daily. Therefore, we investigated whether the daily administration of a low dose of MTX inhibits the progression of arthriti...

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Detalles Bibliográficos
Autores principales: Koyama, Aoi, Tanaka, Aki, To, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Molecular and Clinical Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575561/
https://www.ncbi.nlm.nih.gov/pubmed/28560778
http://dx.doi.org/10.1111/jphp.12752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575561/
https://www.ncbi.nlm.nih.gov/pubmed/28560778
http://dx.doi.org/10.1111/jphp.12752

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