Localization of VEGF to Vascular ECM Is an Important Aspect of Tumor Angiogenesis

Our research has identified several examples in which reduced VEGF-A binding to deficient vascular extracellular matrix leads to deficits in tumor vascularization and tumor growth: (1) germline ablation of collagen VI in the stroma of intracranial B16F10 melanomas; (2) knockdown of the Tks5 scaffold...

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Detalles Bibliográficos
Autores principales: You, Weon-Kyoo, Stallcup, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575600/
https://www.ncbi.nlm.nih.gov/pubmed/28788063
http://dx.doi.org/10.3390/cancers9080097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575600/
https://www.ncbi.nlm.nih.gov/pubmed/28788063
http://dx.doi.org/10.3390/cancers9080097

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