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Localization of VEGF to Vascular ECM Is an Important Aspect of Tumor Angiogenesis
Our research has identified several examples in which reduced VEGF-A binding to deficient vascular extracellular matrix leads to deficits in tumor vascularization and tumor growth: (1) germline ablation of collagen VI in the stroma of intracranial B16F10 melanomas; (2) knockdown of the Tks5 scaffold...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575600/ https://www.ncbi.nlm.nih.gov/pubmed/28788063 http://dx.doi.org/10.3390/cancers9080097 |