Performance of a RT-PCR Assay in Comparison to FISH and Immunohistochemistry for the Detection of ALK in Non-Small Cell Lung Cancer

Patients with lung cancers harboring an activating anaplastic lymphoma kinase (ALK) rearrangement respond favorably to ALK inhibitor therapy. Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) are validated and widely used screening tests for ALK rearrangements but both methods...

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Detalles Bibliográficos
Autores principales: Hout, David R., Schweitzer, Brock L., Lawrence, Kasey, Morris, Stephan W., Tucker, Tracy, Mazzola, Rosetta, Skelton, Rachel, McMahon, Frank, Handshoe, John, Lesperance, Mary, Karsan, Aly, Saltman, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575602/
https://www.ncbi.nlm.nih.gov/pubmed/28763012
http://dx.doi.org/10.3390/cancers9080099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575602/
https://www.ncbi.nlm.nih.gov/pubmed/28763012
http://dx.doi.org/10.3390/cancers9080099

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