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Gut Microbiota is critical for the induction of chemotherapy-induced pain

Chemotherapy-induced pain is a dose-limiting condition that affects 30% of patients undergoing chemotherapy. We found that the gut microbiota promotes the development of chemotherapy-induced mechanical hyperalgesia. Oxaliplatin-induced mechnical hyperalgesia was reduced in germ-free mice and in thos...

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Detalles Bibliográficos
Autores principales: Shen, Shiqian, Lim, Grewo, You, Zerong, Ding, Weihua, Huang, Peigen, Ran, Chongzhao, Doheny, Jason, Caravan, Peter, Tate, Samuel, Hu, Kun, Kim, Hyangin, McCabe, Michael, Huang, Bo, Xie, Zhongcong, Kwon, Douglas, Chen, Lucy, Mao, Jianren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575957/
https://www.ncbi.nlm.nih.gov/pubmed/28714953
http://dx.doi.org/10.1038/nn.4606