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In silico prediction of novel therapeutic targets using gene–disease association data

BACKGROUND: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for efficacy reasons showing poor association between the drug target and the disease. Computational prediction of successful targets could have a considerab...

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Detalles Bibliográficos
Autores principales: Ferrero, Enrico, Dunham, Ian, Sanseau, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576250/
https://www.ncbi.nlm.nih.gov/pubmed/28851378
http://dx.doi.org/10.1186/s12967-017-1285-6