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In silico prediction of novel therapeutic targets using gene–disease association data
BACKGROUND: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for efficacy reasons showing poor association between the drug target and the disease. Computational prediction of successful targets could have a considerab...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576250/ https://www.ncbi.nlm.nih.gov/pubmed/28851378 http://dx.doi.org/10.1186/s12967-017-1285-6 |