Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production

BACKGROUND: P-113 (AKRHHGYKRKFH-NH2) is a 12-amino-acid histidine-rich peptide derived from histatin 5 that is highly degradable in high salt concentrations and biological fluids such as serum, plasma and saliva. Nal-P-113, a novel antimicrobial peptide whose histidine residues are replaced by the b...

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Detalles Bibliográficos
Autores principales: Wang, Hong-yan, Lin, Li, Fu, Wei, Yu, Hui-Yuan, Yu, Ning, Tan, Li-si, Cheng, Jya-wei, Pan, Ya-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576277/
https://www.ncbi.nlm.nih.gov/pubmed/28851350
http://dx.doi.org/10.1186/s12906-017-1931-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576277/
https://www.ncbi.nlm.nih.gov/pubmed/28851350
http://dx.doi.org/10.1186/s12906-017-1931-9

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