β(3) phosphorylation of platelet α(IIb)β(3) is crucial for stability of arterial thrombus and microparticle formation in vivo

BACKGROUND: It is well accepted that functional activity of platelet integrin α(IIb)β(3) is crucial for hemostasis and thrombosis. The β(3) subunit of the complex undergoes tyrosine phosphorylation shown to be critical for outside-in integrin signaling and platelet clot retraction ex vivo. However,...

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Detalles Bibliográficos
Autores principales: Feng, Weiyi, Valiyaveettil, Manojkumar, Dudiki, Tejasvi, Mahabeleshwar, Ganapati H., Andre, Patrick, Podrez, Eugene A., Byzova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576334/
https://www.ncbi.nlm.nih.gov/pubmed/28860945
http://dx.doi.org/10.1186/s12959-017-0145-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576334/
https://www.ncbi.nlm.nih.gov/pubmed/28860945
http://dx.doi.org/10.1186/s12959-017-0145-1

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