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Molecular targeting in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogenous disease associated with distinct genetic and molecular abnormalities. Somatic mutations result in dysregulation of intracellular signaling pathways, epigenetics, and apoptosis of the leukemia cells. Understanding the basis for the dysregulated processes...

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Detalles Bibliográficos
Autores principales: Lim, Seah H., Dubielecka, Patrycja M., Raghunathan, Vikram M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576374/
https://www.ncbi.nlm.nih.gov/pubmed/28851395
http://dx.doi.org/10.1186/s12967-017-1281-x