Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

The modulation of protein–protein interactions (PPIs) represents a major challenge in modern chemical biology. Current approaches (e.g. high-throughput screening, computer aided ligand design) are recognised as having limitations in terms of identification of hit matter. Considerable success has bee...

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Detalles Bibliográficos
Autores principales: Burslem, George M., Kyle, Hannah F., Nelson, Adam, Edwards, Thomas A., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576430/
https://www.ncbi.nlm.nih.gov/pubmed/28878873
http://dx.doi.org/10.1039/c7sc00388a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576430/
https://www.ncbi.nlm.nih.gov/pubmed/28878873
http://dx.doi.org/10.1039/c7sc00388a

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