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Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM(2.5), Budesonide, and Cotreated Exposures

ATP-binding cassette subfamily C (ABCC) genes code for phase III metabolism proteins that translocate xenobiotic (e.g., particulate matter 2.5 (PM(2.5))) and drug metabolites outside the cells. IL-6 secretion is related with the activation of the ABCC transporters. This study assesses ABCC1–4 gene e...

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Detalles Bibliográficos
Autores principales: Encarnación-Medina, Jarline, Rodríguez-Cotto, Rosa I., Bloom-Oquendo, Joseph, Ortiz-Martínez, Mario G., Duconge, Jorge, Jiménez-Vélez, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576432/
https://www.ncbi.nlm.nih.gov/pubmed/28900313
http://dx.doi.org/10.1155/2017/6827194