Brief Report: Selection of HIV-1 Variants With Higher Transmission Potential by 1% Tenofovir Gel Microbicide

BACKGROUND: Women in the CAPRISA 004 trial assigned to use 1% tenofovir (TFV) microbicide gel, who became HIV-1 infected, had higher viral load set-point and slower antibody avidity maturation compared with placebo participants. We investigated whether TFV gel was selected for viruses with altered g...

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Detalles Bibliográficos
Autores principales: Ngandu, Nobubelo K., Carlson, Jonathan M., Chopera, Denis R., Ndabambi, Nonkululeko, Abdool Karim, Quarraisha, Abdool Karim, Salim, Williamson, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2017
Materias:
Prevention Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576519/
https://www.ncbi.nlm.nih.gov/pubmed/28797020
http://dx.doi.org/10.1097/QAI.0000000000001458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576519/
https://www.ncbi.nlm.nih.gov/pubmed/28797020
http://dx.doi.org/10.1097/QAI.0000000000001458

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