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Allosteric Modulators of the CB(1) Cannabinoid Receptor: A Structural Update Review
In 2005, the first evidence of an allosteric binding site at the CB(1)R was provided by the identification of three indoles of the company Organon that were allosteric enhancers of agonist binding affinity and, functionally, allosteric inhibitors of agonist activity. Since then, structure–activity r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576597/ https://www.ncbi.nlm.nih.gov/pubmed/28861476 http://dx.doi.org/10.1089/can.2015.0005 |