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Allosteric Modulators of the CB(1) Cannabinoid Receptor: A Structural Update Review

In 2005, the first evidence of an allosteric binding site at the CB(1)R was provided by the identification of three indoles of the company Organon that were allosteric enhancers of agonist binding affinity and, functionally, allosteric inhibitors of agonist activity. Since then, structure–activity r...

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Detalles Bibliográficos
Autores principales: Morales, Paula, Goya, Pilar, Jagerovic, Nadine, Hernandez-Folgado, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576597/
https://www.ncbi.nlm.nih.gov/pubmed/28861476
http://dx.doi.org/10.1089/can.2015.0005

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