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Endothelial-derived extracellular matrix ameliorate the stemness deprivation during ex vivo expansion of mouse bone marrow-derived mesenchymal stem cells

Mesenchymal stem cells (MSCs) hold great potential in cell therapies by virtue of the regenerative effects and immunomodulatory properties, but the scarce nature of MSCs makes ex vivo expansion indispensable prior to transplantation purposes. However, potential loss of stemness ensuing culture expan...

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Detalles Bibliográficos
Autores principales: Lee, Ming-Kang, Lin, Shau-Ping, HuangFu, Wei-Chun, Yang, Dee-Shiuh, Liu, I-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576725/
https://www.ncbi.nlm.nih.gov/pubmed/28854282
http://dx.doi.org/10.1371/journal.pone.0184111