Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy

Metabolism plays a fundamental role in supporting the growth, proliferation and effector functions of T cells. We investigated the impact of HIV infection on key processes that regulate glucose uptake and mitochondrial biogenesis in subpopulations of CD4+ and CD8+ T cells from 18 virologically-suppr...

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Detalles Bibliográficos
Autores principales: Masson, Jesse J. R., Murphy, Andrew J., Lee, Man K. S., Ostrowski, Matias, Crowe, Suzanne M., Palmer, Clovis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576743/
https://www.ncbi.nlm.nih.gov/pubmed/28854263
http://dx.doi.org/10.1371/journal.pone.0183931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576743/
https://www.ncbi.nlm.nih.gov/pubmed/28854263
http://dx.doi.org/10.1371/journal.pone.0183931

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