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Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans
Sirtuins are NAD⁺-dependent deacetylases, lipoamidases, and ADP-ribosyltransferases that link cellular metabolism to multiple intracellular pathways that influence processes as diverse as cell survival, longevity, and cancer growth. Sirtuins influence the extent of neuronal death in stroke. However,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576752/ https://www.ncbi.nlm.nih.gov/pubmed/28820880 http://dx.doi.org/10.1371/journal.pgen.1006965 |