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The Impact of Base Excision DNA Repair in Age-Related Neurodegenerative Diseases
The aging process and several age-related neurodegenerative disorders have been linked to elevated levels of DNA damage induced by ROS and deficiency in DNA repair mechanisms. DNA damage induced by ROS is a byproduct of cellular respiration and accumulation of damage over time, is a fundamental aspe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576886/ https://www.ncbi.nlm.nih.gov/pubmed/26255938 http://dx.doi.org/10.1016/j.mrfmmm.2014.12.011 |