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Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice

Pancreatitis is a debilitating disease of the exocrine pancreas that, under chronic conditions, is a major susceptibility factor for pancreatic ductal adenocarcinoma (PDAC). Although down-regulation of genes that promote the mature acinar cell fate is required to reduce injury associated with pancre...

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Detalles Bibliográficos
Autores principales: Fazio, Elena N., Young, Claire C., Toma, Jelena, Levy, Michael, Berger, Kurt R., Johnson, Charis L., Mehmood, Rashid, Swan, Patrick, Chu, Alphonse, Cregan, Sean P., Dilworth, F. Jeffrey, Howlett, Christopher J., Pin, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576899/
https://www.ncbi.nlm.nih.gov/pubmed/28701342
http://dx.doi.org/10.1091/mbc.E17-04-0254