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Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice
Pancreatitis is a debilitating disease of the exocrine pancreas that, under chronic conditions, is a major susceptibility factor for pancreatic ductal adenocarcinoma (PDAC). Although down-regulation of genes that promote the mature acinar cell fate is required to reduce injury associated with pancre...
Autores principales: | Fazio, Elena N., Young, Claire C., Toma, Jelena, Levy, Michael, Berger, Kurt R., Johnson, Charis L., Mehmood, Rashid, Swan, Patrick, Chu, Alphonse, Cregan, Sean P., Dilworth, F. Jeffrey, Howlett, Christopher J., Pin, Christopher L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576899/ https://www.ncbi.nlm.nih.gov/pubmed/28701342 http://dx.doi.org/10.1091/mbc.E17-04-0254 |
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