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DNA damage regulates direct association of TOR kinase with the RNA polymerase II–transcribed HMO1 gene
The mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient sufficiency and cellular stress. When mTORC1 is inhibited, protein synthesis is reduced in an intricate process that includes a concerted down-regulation of genes encoding rRNA and ribosomal proteins. The Saccharomyces cerevisiae...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576907/ https://www.ncbi.nlm.nih.gov/pubmed/28701348 http://dx.doi.org/10.1091/mbc.E17-01-0024 |