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DNA damage regulates direct association of TOR kinase with the RNA polymerase II–transcribed HMO1 gene

The mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient sufficiency and cellular stress. When mTORC1 is inhibited, protein synthesis is reduced in an intricate process that includes a concerted down-regulation of genes encoding rRNA and ribosomal proteins. The Saccharomyces cerevisiae...

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Detalles Bibliográficos
Autores principales:	Panday, Arvind, Gupta, Ashish, Srinivasa, Kavitha, Xiao, Lijuan, Smith, Mathew D., Grove, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576907/ https://www.ncbi.nlm.nih.gov/pubmed/28701348 http://dx.doi.org/10.1091/mbc.E17-01-0024

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