Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia

B acute lymphoblastic leukemia (B-ALL) cells are distinctively vulnerable to endoplasmic reticulum (ER) stress. Recently, inhibition of p97 was shown to induce ER stress and subsequently cell death in solid tumors and in multiple myeloma. We investigated the role of a novel, orally available, p97 in...

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Detalles Bibliográficos
Autores principales: Gugliotta, Gabriele, Sudo, Makoto, Cao, Qi, Lin, De-Chen, Sun, Haibo, Takao, Sumiko, Le Moigne, Ronan, Rolfe, Mark, Gery, Sigal, Müschen, Markus, Cavo, Michele, Koeffler, H. Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576979/
https://www.ncbi.nlm.nih.gov/pubmed/28843399
http://dx.doi.org/10.1016/j.neo.2017.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576979/
https://www.ncbi.nlm.nih.gov/pubmed/28843399
http://dx.doi.org/10.1016/j.neo.2017.08.001

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