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Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells

Evidence from animal studies suggests that stress-induced increases in Nrf2-regulated antioxidant gene expression, a critical mechanism of cellular protection, declines with aging. This study examined whether this also occurs in humans. We measured the basal and inducible levels of Nrf2-regulated an...

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Detalles Bibliográficos
Autores principales: Zhou, Lulu, Zhang, Hongqiao, Davies, Kelvin J.A., Forman, Henry Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576992/
https://www.ncbi.nlm.nih.gov/pubmed/28863281
http://dx.doi.org/10.1016/j.redox.2017.08.014