Metabolic and transcriptomic analysis of Huntington’s disease model reveal changes in intracellular glucose levels and related genes

Huntington’s Disease (HD) is a neurodegenerative disorder caused by an expansion in a CAG-tri-nucleotide repeat that introduces a poly-glutamine stretch into the huntingtin protein (mHTT). Mutant huntingtin (mHTT) has been associated with several phenotypes including mood disorders and depression. A...

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Detalles Bibliográficos
Autores principales: Chaves, Gepoliano, Özel, Rıfat Emrah, Rao, Namrata V, Hadiprodjo, Hana, Costa, Yvonne Da, Tokuno, Zachary, Pourmand, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576993/
https://www.ncbi.nlm.nih.gov/pubmed/28920088
http://dx.doi.org/10.1016/j.heliyon.2017.e00381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576993/
https://www.ncbi.nlm.nih.gov/pubmed/28920088
http://dx.doi.org/10.1016/j.heliyon.2017.e00381

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