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Metabolic and transcriptomic analysis of Huntington’s disease model reveal changes in intracellular glucose levels and related genes

Huntington’s Disease (HD) is a neurodegenerative disorder caused by an expansion in a CAG-tri-nucleotide repeat that introduces a poly-glutamine stretch into the huntingtin protein (mHTT). Mutant huntingtin (mHTT) has been associated with several phenotypes including mood disorders and depression. A...

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Detalles Bibliográficos
Autores principales:	Chaves, Gepoliano, Özel, Rıfat Emrah, Rao, Namrata V, Hadiprodjo, Hana, Costa, Yvonne Da, Tokuno, Zachary, Pourmand, Nader
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576993/ https://www.ncbi.nlm.nih.gov/pubmed/28920088 http://dx.doi.org/10.1016/j.heliyon.2017.e00381

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