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Library siRNA-generating RNA nanosponges for gene silencing by complementary rolling circle transcription
Since the discovery of RNA interference (RNAi), small interfering RNA (siRNA) has been powerful tools for gene downregulation in biomedical applications. Despite the outstanding efficacy of siRNA, the development of a therapeutic delivery system remains a challenge owing to the instability of RNA. I...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577100/ https://www.ncbi.nlm.nih.gov/pubmed/28855687 http://dx.doi.org/10.1038/s41598-017-10219-y |