Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ

Fibrosis is a common driver of end-stage organ failure in most organs. It is characterised by excessive accumulation of extracellular matrix (ECM) proteins. Therapeutic options are limited and novel treatments are urgently required, however current cell-based high-throughput screening (HTS) models t...

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Detalles Bibliográficos
Autores principales: Holdsworth, Gill, Bon, Hélène, Bergin, Marianne, Qureshi, Omar, Paveley, Ross, Atkinson, John, Huang, Linghong, Tewari, Roohi, Twomey, Breda, Johnson, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577101/
https://www.ncbi.nlm.nih.gov/pubmed/28855577
http://dx.doi.org/10.1038/s41598-017-10298-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577101/
https://www.ncbi.nlm.nih.gov/pubmed/28855577
http://dx.doi.org/10.1038/s41598-017-10298-x

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