Cargando…

Prostaglandin E1 Attenuates Pulmonary Artery Remodeling by Activating Phosphorylation of CREB and the PTEN Signaling Pathway

The depletion of cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) and phosphatase and tensin homolog (PTEN) is the critical mediator of pulmonary arterial hypertension (PAH). We hypothesized that the activation of phosphorylated CREB (pCREB) and PTEN could inhibit the AK...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Ying-Ju, Hsu, Hsao-Hsun, Chang, Gwo-Jyh, Lin, Shu-Hui, Chen, Wei-Jan, Huang, Chung-Chi, Pang, Jong-Hwei S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577102/ https://www.ncbi.nlm.nih.gov/pubmed/28855544 http://dx.doi.org/10.1038/s41598-017-09707-y

Ejemplares similares

Author Correction: Prostaglandin E1 Attenuates Pulmonary Artery Remodeling by Activating Phosphorylation of CREB and the PTEN Signaling Pathway
por: Lai, Ying-Ju, et al.
Publicado: (2018)

Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase
por: Lai, Ying-Ju, et al.
Publicado: (2015)

Sirolimus Suppresses Phosphorylation of Cofilin and Reduces Interstitial Septal Thickness in Sporadic Lymphangioleiomyomatosis
por: Huang, Yen-Lin, et al.
Publicado: (2021)

PTEN participates in airway remodeling of asthma by regulating CD38/Ca(2+)/CREB signaling
por: Wu, Yuanyuan, et al.
Publicado: (2020)

Molecular Mechanisms Underlying Remodeling of Ductus Arteriosus: Looking beyond the Prostaglandin Pathway
por: Hsu, Ho-Wei, et al.
Publicado: (2021)

Candesartan Cilexetil Attenuates Arrhythmogenicity Following Pressure Overload in Rats via the Modulation of Cardiac Electrical and Structural Remodeling and Calcium Handling Dysfunction
por: Chang, Gwo‐Jyh, et al.
Publicado: (2022)

Shikonin Attenuates Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment by Inhibiting Apoptosis via PTEN/Akt/CREB/BDNF Signaling
por: Jia, Yanqiu, et al.
Publicado: (2021)

In vivo imaging of CREB phosphorylation in awake-mouse brain
por: Ishimoto, Tetsuya, et al.
Publicado: (2015)

Triptans attenuate capsaicin-induced CREB phosphorylation within the trigeminal nucleus caudalis: a mechanism to prevent central sensitization?
por: Mitsikostas, Dimos D., et al.
Publicado: (2011)

Dipyridamole induces the phosphorylation of CREB to promote cancer cell proliferation
por: Abdelghany, Lina, et al.
Publicado: (2021)

Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning
por: Soleimanpour, Elaheh, et al.
Publicado: (2021)

Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies
por: Wu, Yu, et al.
Publicado: (2023)

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts
por: Chang, Chung-Hsun, et al.
Publicado: (2014)

Long noncoding RNA GAS5 attenuates cigarettesmoke-induced airway remodeling by regulatingmiR-217-5p/PTEN axis : GAS5 attenuates airway remodeling by miR-217-5p/PTEN axis
por: Du, Yong, et al.
Publicado: (2022)

AKT1-CREB stimulation of PDGFRα expression is pivotal for PTEN deficient tumor development
por: Wan, Xiaofeng, et al.
Publicado: (2021)

PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo
por: Chiang, Kun-Chun, et al.
Publicado: (2015)

Role of the Phosphatase PTEN in Early Vascular Remodeling
por: Sedding, Daniel G., et al.
Publicado: (2013)

Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus
por: Cheng, Che-Chih, et al.
Publicado: (2022)

Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior
por: Briand, Lisa A., et al.
Publicado: (2015)

Phosphorylation of CREB at Serine 142 and 143 Is Essential for Visual Cortex Plasticity
por: Pulimood, Nisha S., et al.
Publicado: (2021)

CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells
por: Pittari, Daniele, et al.
Publicado: (2022)

Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
por: Kwon, Hyun Jung, et al.
Publicado: (2019)

Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway
por: Hsieh, Ming-Jer, et al.
Publicado: (2020)

Learning and Nicotine Interact to Increase CREB Phosphorylation at the jnk1 Promoter in the Hippocampus
por: Kenney, Justin W., et al.
Publicado: (2012)

Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets
por: Barbosa, Sónia, et al.
Publicado: (2015)

MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
por: Li, Jianchang, et al.
Publicado: (2019)

Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages
por: Selezneva, Anna, et al.
Publicado: (2021)

Structural and Dynamic Effects of PTEN C-Terminal Tail Phosphorylation
por: Smith, Iris N., et al.
Publicado: (2022)

Unexpected cardio‐circulatory arrest during a brain‐dead donor organ retrieval
por: Chen, Pei‐Hsing, et al.
Publicado: (2021)

PTEN‐AKT pathway attenuates apoptosis and adverse remodeling in ponatinib‐induced skeletal muscle toxicity following BMP‐7 treatment
por: Srivastava, Ayushi, et al.
Publicado: (2023)

Temporal Decoding of MAP Kinase and CREB Phosphorylation by Selective Immediate Early Gene Expression
por: Saito, Takeshi H., et al.
Publicado: (2013)

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1
por: Berto, Melissa, et al.
Publicado: (2018)

Cyclooxygenase and Prostaglandin in Cancer
por: Kim, Jong-Woo
Publicado: (2012)

NMDA receptor mediates proliferation and CREB phosphorylation in postnatal Müller glia-derived retinal progenitors
por: Ramírez, Mónica, et al.
Publicado: (2009)

Involvement of phosphorylated Apis mellifera CREB in gating a honeybee's behavioral response to an external stimulus
por: Gehring, Katrin B., et al.
Publicado: (2016)

Polydatin down-regulates the phosphorylation level of Creb and induces apoptosis in human breast cancer cell
por: Chen, Sijia, et al.
Publicado: (2017)

Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis
por: Bolduc, David, et al.
Publicado: (2013)

Pneumopericardium secondary to oesophageal cancer presenting as myocardial infarction: a case report
por: Shih, Yu‐Shan, et al.
Publicado: (2021)

Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling
por: Yin, Ping, et al.
Publicado: (2021)

Low-Level Laser Irradiation Stimulates Tenocyte Migration with Up-Regulation of Dynamin II Expression
por: Tsai, Wen-Chung, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_cvtn8c9ejgnh067t15s0u721vg