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Enhanced antitumor effect on intrapulmonary tumors of docetaxel lung-targeted liposomes in a rabbit model of VX2 orthotopic lung cancer

Allergic reactions and severe systemic toxicity are two major challenges for the clinical application of docetaxel (DTX) for treatment of non-small-cell lung cancer (NSCLC). We developed a novel lung-targeted DTX-loaded liposome (DTX-LP), an efficient drug delivery system, with a patented DBaumNC te...

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Detalles Bibliográficos
Autores principales: Wang, LiJuan, Li, Rui, Che, KeKe, Liu, ZhongHong, Xiang, ShiFeng, Li, MengYa, Yu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577178/
https://www.ncbi.nlm.nih.gov/pubmed/28855665
http://dx.doi.org/10.1038/s41598-017-10530-8