Nucleolar expansion and elevated protein translation in premature aging

Premature aging disorders provide an opportunity to study the mechanisms that drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins. We sought to investigate protein homeostasis in this disea...

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Detalles Bibliográficos
Autores principales: Buchwalter, Abigail, Hetzer, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577202/
https://www.ncbi.nlm.nih.gov/pubmed/28855503
http://dx.doi.org/10.1038/s41467-017-00322-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577202/
https://www.ncbi.nlm.nih.gov/pubmed/28855503
http://dx.doi.org/10.1038/s41467-017-00322-z

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