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Primary patient-derived lung adenocarcinoma cell culture challenges the association of cancer stem cells with epithelial-to-mesenchymal transition

The cancer stem cell (CSC) and epithelial-to-mesenchymal transition (EMT) models have been closely associated and used to describe both the formation of metastasis and therapy resistance. We established a primary lung cell culture from a patient in a clinically rare and unique situation of primary r...

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Detalles Bibliográficos
Autores principales: Tiran, Verena, Lindenmann, Joerg, Brcic, Luka, Heitzer, Ellen, Stanzer, Stefanie, Tabrizi-Wizsy, Nassim Ghaffari, Stacher, Elvira, Stoeger, Herbert, Popper, Helmut H., Balic, Marija, Dandachi, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577216/
https://www.ncbi.nlm.nih.gov/pubmed/28855609
http://dx.doi.org/10.1038/s41598-017-09929-0