Celecoxib normalizes the tumor microenvironment and enhances small nanotherapeutics delivery to A549 tumors in nude mice

Barriers presented by the tumor microenvironment including the abnormal tumor vasculature and interstitial matrix invariably lead to heterogeneous distribution of nanotherapeutics. Inspired by the close association between cyclooxygenase-2 (COX-2) and tumor-associated angiogenesis, as well as tumor...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Jin, Kai, Jiang, Ting, Wang, Lanting, Shen, Shun, Luo, Zimiao, Tuo, Yanyan, Liu, Xianping, Hu, Yu, Pang, Zhiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577220/
https://www.ncbi.nlm.nih.gov/pubmed/28855534
http://dx.doi.org/10.1038/s41598-017-09520-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577220/
https://www.ncbi.nlm.nih.gov/pubmed/28855534
http://dx.doi.org/10.1038/s41598-017-09520-7

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